True B6 …pure Pyridoxal 5-Phosphate (P5P)
The True, Enzymatic form of Vitamin B6 can help:
More people are beginning to appreciate the difference between the active, enzymatic form of Vitamin B6 and the inactive chemical analogs that often are sold as Vitamin B6. When a Vitamin B6 deficiency is suspected, P5P is the clear choice.
Summary
Vitamin B6 is indisputably needed for amino-acid metabolism, cardiovascular health, and nervous-system function, and much more. Although it is found in nearly every multi-vitamin supplement, the synthetic form of vitamin B6 (pyridoxine HCl) cannot be used by your body without a chemical conversion known as “phosphorylation.” Researchers believe, however, that phosphorylation can be impaired by infection… even common infections, such as candidiasis. Furthermore, when the synthetic form is not converted to the active form (pyridoxal 5-phosphate), researchers speculate that it may interfere with vitamin B6 receptor sites, possibly worsening a deficiency rather than correcting it.
Explanation
Every amino-acid pathway requires enzymatic vitamin B6 for proper metabolism. Coenzymes (often vitamins) frequently are critical to the performance of an enzyme, and together they catalyze the biochemistry of life. In order to work properly, however, the correct form or “orthomolecular” form of the vitamin must be available. In the world of “bargain” nutritional supplements, however, ingredients often are called something they are not. Thus, a synthetic vitamin-analog can be called a vitamin simply because it contains a component of the true vitamin. Pure, pyridoxal 5-phosphate is the True vitamin B6.
A Short Bibliography
J. Shen, C.-Q. Lai, J. Mattei, J. M Ordovas, and K. L Tucker. Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study, Am. J. Clinical Nutrition, February 1, 2010; 91(2): 337 – 342.
Pedersen, and O. Nygard Mortality and Cardiovascular Events in Patients Treated With Homocysteine-Lowering B Vitamins After Coronary Angiography: A Randomized Controlled Trial JAMA, August 20, 2008; 300(7): 795 – 804.
A. T Vasilaki, D. C McMillan, J. Kinsella, A. Duncan, D. S. J O’Reilly, and D. Talwar. Relation between pyridoxal and pyridoxal phosphate concentrations in plasma, red cells, and white cells in patients with critical illness, Am. J. Clinical Nutrition, July 1, 2008; 88(1): 140 – 146.
European Journal of biochemistry, Volume 219 Issue 3, Pages 953 – 960.
Annual Review of Medicine, Vol. 49: 31-62 (Volume publication date February 1998).
If pregnant, lactating, taking medications, or you have special food sensitivities, please check with your pharmacist or physician.
Recommended Dosage:
Take one (1) capsule per day or as directed by your doctor.
Only the natural form of Vitamin B-6 is used by your cells for over 100 enzymes critical to all amino-acid metabolism.
